Malathy Shanmugam, PhD

Assistant Professor, Hematology & Medical Oncology

Emory University School of Medicine

Office: Winship Cancer Institute of Emory University

Phone: (404) 778-5871

Fax: (404) 778-5520

Email: mala.shan@emory.edu

Biography

Malathy Shanmugam, PhD, MS, is an Assistant Professor in the Department of Hematology and Medical Oncology at Emory School of Medicine. Dr. Shanmugam is a member of the Cancer Cell Biology Research Program at Winship Cancer Institute.

Dr. Shanmugam attended Madurai Kamaraj University in T. Nadu, India where she earned a MS in Biotechnology. She received her PhD in Tumor Cell Biology from Northwestern University Medical School in Chicago, IL. She completed her fellowship training at Northwestern University Medical School and at Loyola University of Chicago Medical Center.

Research

Investigating mechanisms underlying abnormal glucose utilization and the impact of enhanced glucose utilization on cell survival and proliferation in the hematologic malignancies multiple myeloma (MM) and CLL. The long-term objectives of my research are to 1) Improve our understanding of the molecular and cellular basis of enhanced glucose utilization in myeloma and other glycolytic cancers 2) Elucidate molecular mechanisms contributing to apoptosis sensitivity following GLUT4 inhibition in multiple myeloma and 3) Demonstrate the feasibility and therapeutic promise of targeting GLUT4 in myeloma by employing in vivo disease models and generation of selective GLUT4 inhibitors 4) Explore biological functions of novel glucose transporters 8 and 11 in myeloma pathobiology.

Publications