The faculty of the Hematology and Medical Oncology Department consists of clinical and basic science investigators who conduct a broad range of basic, translational and clinical research on a variety of human malignancies. Our faculty members make cutting edge discoveries that lead to better understanding and improved detection and treatment of cancer.
Our basic research covers genetic and biochemical foundations of cancer, from the identification of oncogenes and tumor suppressor genes to their functional characterization in various models such as genetically modified mouse models. Multiple investigators are working to discover novel signaling pathways underlying the proliferation, differentiation, apoptosis and metastasis of cancer cells, which could potentially lead to the identification of novel targets for therapeutic intervention.
As a clinical department, we have a broad range of clinical studies, including a large number of clinical trials that are conducted to evaluate new drugs/agents, new devices, new regimens, and new strategies for the treatment and prevention of cancer. We also develop and design cutting edge ethical research in order to ensure that our clinical research is ethical.
The Department has a broad range of translational studies among the faculty members. Chemoprevention is one such area of study. Natural dietary compounds as well as synthetic chemicals are being evaluated for their roles in the prevention of tumor development and progression from premalignant lesion to invasive cancer to metastasis, in addition to the identification of molecular targets. Epigenetic strategies are also applied.